Characterisation of an avian influenza A virus isolated from a human – is an intermediate host necessary for the emergence of pandemic influenza viruses?
Identifieur interne : 001B14 ( Main/Exploration ); précédent : 001B13; suivant : 001B15Characterisation of an avian influenza A virus isolated from a human – is an intermediate host necessary for the emergence of pandemic influenza viruses?
Auteurs : J. Banks [Royaume-Uni] ; E. Speidel [Royaume-Uni] ; D. J. Alexander [Royaume-Uni]Source :
- Archives of Virology [ 0304-8608 ] ; 1998-04-01.
Abstract
Summary: The partial sequencing of the internal and the neuraminidase genes of isolate 268/96 obtained from a woman with conjunctivitis showed all seven to have closest homology with avian influenza viruses. The entire nucleotide sequence of the haemagglutinin gene of 268/96 had close, 98.2%, homology with an H7N7 virus isolated from turkeys in Ireland in 1995. This appears to be the first reported case of isolation of an influenza A virus from a human being infected as a result of direct natural transmission of an avian influenza virus from birds.
Url:
DOI: 10.1007/s007050050329
Affiliations:
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<front><div type="abstract" xml:lang="en">Summary: The partial sequencing of the internal and the neuraminidase genes of isolate 268/96 obtained from a woman with conjunctivitis showed all seven to have closest homology with avian influenza viruses. The entire nucleotide sequence of the haemagglutinin gene of 268/96 had close, 98.2%, homology with an H7N7 virus isolated from turkeys in Ireland in 1995. This appears to be the first reported case of isolation of an influenza A virus from a human being infected as a result of direct natural transmission of an avian influenza virus from birds.</div>
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